Cancer And Inflammation (Novartis Foundation Symposia)

 Cancer and Inflammation (Novartis Foundation Symposia) PDF ePub fb2 book

Chronic inflammation predisposes to some forms of cancer and thehost response to malignant disease shows several parallels withinflammation and wound healing. The cells involved in inflammationare detected in a range of common cancers, together with theinflammatory cytokines and members of the chemokine ligand/receptorsystems.Neutralization or deletion of the gene for some inflammatorycytokines co...

Series: Novartis Foundation Symposia (Book 256)
Hardcover: 290 pages
Publisher: Wiley; 1 edition (March 5, 2004)
Language: English
ISBN-10: 047085510X
ISBN-13: 978-0470855102
Product Dimensions: 6.3 x 0.7 x 9.3 inches
Amazon Rank: 8434091
Format: PDF ePub Text TXT fb2 ebook

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tance to tumour induction and experimentalmetastasis. Over-expression of such cytokines in tumour cells mayenhance malignant potential. Certain chemokines are likely tosubvert antitumour immunity by favouring development of ineffectiveType 2 responses. Tumour cells may even utilize chemokine receptorsin homing to lymph nodes and other organs. Thus, the cells,cytokines and chemokines found in tumours are more likely tocontribute to tumour growth, progression and immunosuppression thanthey are to mount an effective host antitumour response.This book draws together contributions from an international groupof scientists and clinicians from diverse disciplines, ranging fromepidemiology to immunology, cell biology, molecular oncology,molecular medicine and pharmacology to debate these and relatedissues. Topics covered include the epidemiological links betweencancer and inflammation, the parallels between inflammation andcancer, the role of inflammation in cancer, inflammatory genes asrisk factors for cancer initiation and progression, inflammationand cancer angiogenesis, and preventative and therapeuticstrategies.Related Novartis Foundation symposia:252 Generation and Effector Functions of RegulatoryLymphocytesChair: Jean-François Bach254 Immunoinformatics: Bioinformatic Strategies for BetterUnderstanding of Immune FunctionChair: Hans-Georg Rammensee